Background: Breast cancer is biologically heterogeneous, and altered cell-cycle control contributes to tumour development, proliferation and therapeutic response. Cell-cycle gene expression data from Nigerian women are l Read more

Background: Cancer antigen 15-3 (CA 15-3), a circulating epitope of mucin-1 (MUC1), is used principally to support monitoring of breast cancer, whereas complete blood count indices reflect inflammation, marrow function and tr Read more

Background: Staphylococcus aureus is a major opportunistic pathogen associated with a wide range of clinical infections, while the increasing prevalence of methicillin-resistant S. aureus (MRSA), multidrug resistance, and&nbs Read more

Background: Promyelocytic Leukaemia -Nuclear Bodies (PML-NBs) represent a key component of the innate immune defense against pathogens, including viruses such as Coronavirus 2 (SARS-CoV-2). Aim: Evaluate Read more

Compound odontoma is a malformation typical of young adults, with a slight preference for the male gender and the anterior region of the maxilla. Clinically asymptomatic, it can be detected during a radiological investigation in connecti Read more

Background: Oral health care is an integral component of overall physical well-being and quality of life. Despite its importance, disparities in geographic and socioeconomic access continue to limit the utilization of es Read more

Background: Rheumatoid arthritis (RA) is a chronic autoimmune disease driven by a network of pro-inflammatory cytokines and epigenetic regulators that together sustain synovial inflammation and joint damage. Interleukin- Read more

The health hazards on different organs of the body from the long continuous use of Trona have been the major concern in recent times in Nigeria. This study is to qualitatively and quantitatively analyze three types of Trona to determine Read more

Stafne bone cysts (SBCs) are typically asymptomatic, incidental findings at the mandibular angle, making clinical differentiation from true tumors challenging. We present an atypical case of an SBC presenting with long-standing pain in t Read more

Drug repurposing holds great potential in terms of discovering new anticancer agents via assigning new therapeutic uses to already approved drugs. Through epigenetic regulation of gene expression, histone deacetylase 3 (HDAC3) functions Read more